Key results
The company
Natera
natera.comCell-free DNA testing and diagnostics for oncology, women’s health, and organ health.
Result highlights
- Data extraction increased from 25 to 46 elements
- Recurrence detected up to 9 months earlier
- Potential insight time cut from months to minutes
The story
A global leader in cell-free DNA testing processes over 54,000 tests weekly, generating approximately 1.6 petabytes of complex genomic data across two labs.
Data silos and manual workflows consumed valuable resources, forcing researchers to spend months reviewing medical literature for new test development. This operational friction limited the ability to scale complex analysis operations and deliver rapid results to patients.
The organization automated its genomic pipelines using AWS HealthOmics to handle compute and orchestration, allowing scientists to write workflows in Nextflow without managing infrastructure. A parallel generative AI system uses Amazon Textract and Claude 3.5 Sonnet to extract and analyze unstructured clinical text, storing embeddings in Amazon RDS for semantic search. This architecture is unified within Amazon SageMaker to provide secure data discovery and governance across all research teams.
Quotes
“Our aim is to transform the management of disease, worldwide. This is a bold statement, but our mission is to make personalized genetic testing a standard of care for patients. We can help our patients live longer, healthier lives with more information about their health, and more targeted interventions.”