AI case study

Retro BiosciencesProtein engineering

Navigating 10^1000 variants was impossible. A model designed novel proteins, boosting stem cell marker expression >50x over controls.

Published|9 months ago

Key results

Marker Expression
>50x
vs wild-type controls
Variant Hit Rate
~50%
vs 5% manual success rate
Screen Hit Rate
>30%
vs <10% typical hit rate

Result highlights

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The story

Context

A longevity biotech startup working to extend human healthspan by optimizing the proteins responsible for cellular reprogramming and rejuvenation.

Challenge

The standard reprogramming process is notoriously inefficient, with conversion rates typically below 0.1% and timelines exceeding three weeks....

Solution
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Quotes

The company

Retro Biosciences logo

Retro Biosciences

retro.bio

Biotechnology firm targeting cellular aging to increase healthy human lifespan.

IndustryPharmaceuticals & Biotech
LocationRedwood City, CA, USA
Employees51-250
Founded2021

The vendor

AI research and deployment company developing generative models and tools.

IndustrySoftware & Platforms
LocationSan Francisco, CA, USA
Employees1K-5K
Founded2015

Use case

Retro Biosciences's Protein engineering is part of this use case:

Scientific Discovery
22 case studies(+167% YoY)
Proven impact?
LowModerateVery Strong
4.0Moderate
4.1Moderatewithin Pharmaceuticals & Biotech
3.7Moderatewithin Product Engineering

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